Scientific Background

The core of Optima's intellectual property, Aura, is based on the scientific research initiated by Dr. J. Chris Sackellares and Dr. Leon D. Iasemidis in 1988. They applied techniques for analyzing nonlinear chaotic systems to the study of EEG signals from patients with medically refractory epilepsy. Later, Dr. Sackellares and colleagues at the University of Florida reported evidence that seizures evolve in a characteristic way over minutes to hours and are preceded by a preictal transition that is detectable by monitoring the spatiotemporal features of EEG. These discoveries provide the Company strong scientific rationale for development of brain monitoring systems that will enhance the efficiency and safety in the routine inpatient care of patients with epilepsy or other neurological disorders.